Mike's Notes
This is part of why I rebuilt Pipi 6 from memory.
Resources
- https://en.wikipedia.org/wiki/Markus_W._Covert
- https://www.scientificamerican.com/article.cfm?id=scientists-successfully-model-a-living-cell-with-software
- https://www.covert.stanford.edu/
- https://profiles.stanford.edu/markus-covert
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413483
- https://www.covert.stanford.edu/publications
- https://www.covert.stanford.edu/_files/ugd/f6999c_bd641d2b9dd9443e9ed3768568b50c5c.pdf
- https://www.wholecellviz.org/viz.php
- https://www.blog.ajabbi.com/2014/01/scientists-successfully-model-living.html
- https://www.blog.ajabbi.com/2013/12/a-computational-whole-cell-model.html
References
- Fundamentals of Systems Biology
Repository
- Home > Ajabbi Research > Library > Authors > Markus Covert
- Home > Handbook >
Last Updated
11/05/2025
Markus Covert and Mycoplasma
Mike is the inventor and architect of Pipi and the founder of Ajabbi.
In 2014, I read an article in Scientific American by Markus Covert at Stanford about the successful computer cellular simulation of Mycoplasma. It was a fascinating article that made me think about Pipi and whether it could have been better built during 2005-2008.
When my wife and I left Christchurch in 2014 to start a new life, I became curious about modern cloud computing and read a great deal. Then, I realised that PIPI was a very early form of cloud computing, and many of its features were 10 years ahead of their time. What a waste!
By 2016, I was mad about missing the opportunity and decided to rebuild Pipi as a core platform from memory.
From 2017 to 2019, Pipi 6 was built by fusing the rebuilt core platform with Covert Lab's open-source cellular simulation software. This process was challenging and resulted in an unusual architecture. Every process was given a random probability, with many positive and negative feedback loops. It was like composing music. (In hindsight, synesthesia helped a lot.)
Markus W. Covert (born April 24, 1973)
is a researcher and professor of bioengineering at Stanford University who led the simulation of the first organism in software.[1][2][3] Covert leads an interdisciplinary lab of approximately 10 graduate students and post-doctoral scholars.[4]
It may be interesting to look at Markus recent talk https://www.youtube.com/watch?v=sQCa08U2Ykk
ReplyDeleteThanks Alex, I added the video recording of the talk to this post
ReplyDelete